Stephen Comfort was born in 1810 in the United States, later moving to Canada. He and his wife, Elizabeth, had several children. He died in 1895.
James Greer was born in 1798 in Ireland. He married Ruth Ann Rayers in 1819 and they had several children. He died in 1866 due to an accident when he was thrown from his wagon when his horses spooked.
Stephen Comfort and James Greer ran a carding mill and cloth dressing establishment, sometimes referred to as Comfort & Co. They were located along the Thames River in Kilworth, Ontario, about nine miles from London. Their carding machine was a notable piece of equipment in 1857.